Crosslinking, Labeling and Protein Modification
Medchemexpress LLC Mal-PEG4-bis-PEG4-propargyl | 1060.19 g·mol⁻¹ | C49H81N5O20 | 5 MG
Mal-PEG4-bis-PEG4-propargyl is a cleavable eight-unit polyethylene glycol (PEG) linker designed for bioconjugation applications, especially antibody-drug conjugate (ADC) synthesis. It contains a maleimide group for thiol-selective conjugation and a propargyl (alkyne) handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling modular attachment strategies and click chemistry workflows.
- Cleavable eight-unit PEG linker.
- Maleimide group for thiol-selective conjugation.
- Propargyl (alkyne) handle for CuAAC click chemistry.
- Suitable for ADC and general bioconjugation workflows.
- Available in milligram quantities for research use.
Nacalai USA Inc TURBOTEV (TEV PROTEASE) 1MG
TurboTEV doesn't require any special buffer and can be used in a buffer most suitable for the target protein, It is a 52kDa protein with both GST and His tags so it can be removed by either Ni-chelating or Glutathione resin.
![eMolecules 134179-38-7 | N3-PEG(4)-NH2 | Chem-Impex | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 5g | 490846211](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000189594.jpg-250.jpg)
eMolecules 134179-38-7 | N3-PEG(4)-NH2 | Chem-Impex | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 5g | 490846211
N3-PEG(4)-NH2 | Chem-Impex | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 5g | 490846211
eMolecules 1334177-86-4 | Mal-amido-PEG8-C2-acid | Medchem Express | MFCD13184956 | 592.639 | C26H44N2O13 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 500mg | 705859918
Mal-amido-PEG8-C2-acid | Medchem Express | 1334177-86-4 | MFCD13184956 | 592.639 | C26H44N2O13 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 500mg | 705859918
Bioassay Systems QuantiFluo™ Pepsin Inhibitor Assay Kit, For evaluation of drugs and screening of potential inhibitors to pepsin proteases.
PEPSIN (EC 3.4.23.1) is a digestive, serine protease that hydrolyzes dietary proteins in many eukaryotic and prokaryotic organisms. Pepsin predominantly cleaves peptide chains at the amino side of the aromatic phenylalanine, tryptophan, and tyrosine amino acids. BioAssay Systems’ QuantiFluo™ Pepsin Inhibitor Assay Kit uses a fluorescein isothiocyanate (FITC)-labeled synthetic substrate. The fluorescein label is highly quenched. Upon digestion by pepsin present in the sample, the substrate is cleaved into smaller peptides, which abolishes the quenching of the fluorescence label. The fluorescence or fluorescence polarization (FP) of the FITC-labeled fragments is measured at λex/em = 485/530 nm. Inhibition is determined by the decrease in fluorescence.
eMolecules 882847-34-9 | FMOC-NH-PEG6-CH2CH2COOH | AstaTech | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 449766659
FMOC-NH-PEG6-CH2CH2COOH | AstaTech | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 449766659
Medchemexpress LLC Mal-PEG24-NHS ester | 2226733-37-3 | MFCD11041160 | 95.0% | 1394.55 | C62H111N3O31 | 5 MG
Mal-PEG24-NHS ester is a bifunctional polyethylene glycol (PEG) linker containing a maleimide and an N-hydroxysuccinimide (NHS) ester. It is designed for bioconjugation and PROTAC synthesis, enabling selective coupling between thiol and primary amine functionalities while improving solubility and molecular flexibility. The compound is an oil (colorless to light yellow) with molecular weight 1394.55 and formula C62H111N3O31.
- Enables selective maleimide-thiol coupling to modify cysteine residues.
- Provides NHS-ester reactivity for efficient labeling of primary amines.
- PEG24 spacer increases solubility and reduces steric hindrance.
- Suitable for assembling heterobifunctional molecules such as PROTACs.
- Stable under sealed storage at -20 °C; in solvent, store at -80 °C for long-term stability.
- Supplied in small research quantities suitable for synthetic applications.
Medchemexpress LLC 3031336-58-7 | 95.6% | 1151.78 | C58H72ClFN12O8S | 5 MG
PROTAC EGFR degrader 2 is a PROTAC designed to selectively degrade the epidermal growth factor receptor (EGFR) and to support biochemical and cellular research into EGFR-driven signaling and antiproliferative effects.
- Potent EGFR degrader with reported DC50 36.51 nM.
- Exhibits antiproliferative activity (IC50 ≈4.0 nM).
- Purity 95.6% suitable for research applications.
- DMSO solubility up to 100 mg/mL; ultrasonic assistance recommended.
- Supplied as a light yellow to yellow solid for handling convenience.
- Store solid at 4°C protected from light; in solution store at -80°C (6 months) or -20°C (1 month).